Retinoids And Carotenoids In Dermatology

This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of

Retinoids: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Retinoids in a concise format. The editors have built Retinoids: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Retinoids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Retinoids: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Vitamin A (retinol) is an essential dietary compound with myriad metabolic and regulatory functions. Deficiency can result in vision problems, compromised immune responses, and a host of other medical issues. More than 600 carotenoids have been identified in plants, algae, fungi, and bacteria, and around 50 carotenoids—including β-carotene—can be converted into vitamin A. Carotenoids and Vitamin A in Translational Medicine reviews the medical use of carotenoids and vitamin A in cancer; diseases of the skin, eye, ear, and lung; and inflammatory bowel and metabolic diseases. It also discusses the analytics of carotenoids and the supply of carotenoids and vitamin A in developing countries. Serving a broad community of researchers and practitioners conducting basic and clinical analysis on carotenoids and vitamin A for medical purposes, the book evaluates basic research, epidemiological studies, and clinical trials in the field. It updates information on the worldwide problem of vitamin A deficiency and discusses extensively the pros and cons of carotenoid supplementation in cancer. The authors provide a comprehensive overview of the efforts made in the field of carotenoid research with respect to translational medicine and present the future outlook on carotenoids as new therapeutic agents. It is the editors’ intent through the contributions in this volume to expand this important discussion on therapeutic approaches using carotenoids and retinoids. In doing so, they hope to enhance the quality of research which brings safe, effective, and clinically proven medicines to patients.

Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

In the Third Edition of Cosmetic Dermatology: Products and Procedures, accomplished dermatologist Dr. Zoe Diana Draelos delivers the latest information on procedural innovations in the rapidly developing field of cosmetic dermatology. This new edition is structured to follow the typical patient’s cosmetic routing, from everyday moisturizing to adornment and anti-aging techniques. It includes summary boxes at the start of each section to allow for quick reference in a clinical setting, over 300 full-color images illustrate procedures, and demonstrates the benefits of cosmetic products and techniques. Cosmetic Dermatology combines the expertise of leaders in research, industry, surgery, and practice to introduce cutting edge concepts and outline the best techniques in the cosmetic field.. It addresses appearance issues affecting the skin, hair, and nails. The new edition offers a complete cosmetic regimen for the patients of any cosmetic dermatologist, whether hospital-based or in private practice. It also provides: A thorough introduction to basic concepts in dermatology, including skin physiology pertinent to cosmetic dermatology and the delivery of cosmetic actives A comprehensive exploration of skin hygiene products, including cleansers, moisturizers, and personal care products Practical discussions of adornments, including colored facial cosmetics, eye cosmetics, camouflaging products, nail cosmetics, and hair cosmetics In-depth examinations of anti-aging products and procedures, including cosmeceuticals, injectable anti-aging techniques, resurfacing techniques, and skin modulation techniques Cosmetic Dermatology is perfect for practicing and academic dermatologists, trainee dermatologists, dermatology nurses, and skin care industry researchers It will also earn a place in the libraries of gynecologists, medical aestheticians, family practitioners, and plastic surgeons.

Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.

Cosmeceuticals – skin care products that fall between a cosmetic and a pharmaceutical, with active ingredients that counter skin aging and promote skin rejuvenation – are an invaluable adjunct to the cosmetic dermatologist or plastic surgeon performing minimally invasive aesthetic procedures. This guide from expert researchers and practitioners explains how best to integrate the potential of cosmeceutical products into the best international clinical practice, with new chapters to cover the very latest developments in this area. The Series in Cosmetic and Laser Therapy is published in association with the Journal of Cosmetic and Laser Therapy.

Basic investigators as well as clinicians will find this volume valuable both as a summary of recent research and as a stimulus for future experimental work in this continuously expanding field.

Retinoids—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Retinoids in a concise format. The editors have built Retinoids—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Retinoids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Retinoids—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Addressing one of the most commonly encountered conditions seen by the dermatologist, this source analyzes the pathophysiology, evaluation, diagnosis, clinical features, and control of acne. With full-color illustrations, this source delves into the available treatment options for difficult cases of acne and scarring and provides expert discussions

This book provides the dermatologist with the essential information needed to properly treat all skin types cosmetically. All chapters have been written by female dermatologists with many years of personal experience in the field. The volume includes an overview of the systemic, intrinsic and extrinsic aging process, essential information on anti-aging skin care product ingredients, detailed discussions of patient selection and indications, and a wide range of cosmetic procedures. This concise book allows you - through its well-organized use of sidebars, photographs and illustrations - to extract any information you may need quickly and easily.

The impact of the retinoids in clinical practice has primarily been in dermatology. When Dr Werner Bollag began his basic research and screening programme in the early 1960's, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (Roaccutane) in the years between 1972 and 1976 in the field of dermatology. In fact the first symposium on retinoid research held in Berlin in 1981 was almost entirely dermatological. A year later a retinoid workshop in Iowa was designed to provide a forum for dermatolog ists from the USA involved in specific protocols investigating oral retinoids. In the UK, research into the retinoids began rather later than in Continental Europe or in the USA, although Tigason was first marketed here. It was felt in late 1982 that as many dermatologists had relatively little experience with these compounds it would be appropriate to hold an International Symposium on retinoid therapy in the UK. Thus on 16-18 May 1983 in London, 37 speakers from 11 countries addressed an audience of 300, aminly UK, dermatologists. The scientific organizing committee consisted of but two persons Dr William Cunliffe of Leeds General Infirmary, representing the European Society of Dermatolo gical Research, and myself from Roche Clinical Research. The Symposium was held under the auspices of the ESDR and of Roche Products Limited.

The vitamins are a chemically disparate group of compounds whose only common feature is that they are dietary essentials that are required in small amounts for the normal functioning of the body and maintenance of metabolic integrity. Metabolically they have diverse function, as coenzymes, hormones, antioxidants, mediators of cell signaling and regulators of cell and tissue growth and differentiation. This book explores the known biochemical functions of the vitamins, the extent to which we can explain the effects of deficiency or excess and the scientific basis for reference intakes for the prevention of deficiency and promotion of optimum health and well-being. It also highlights areas where our knowledge is lacking and further research is required. It provides a compact and authoritative reference volume of value to students and specialists alike in the field of nutritional biochemistry, and indeed all who are concerned with vitamin nutrition, deficiency and metabolism.

This book compiles the best evidence in procedural dermatology, including skin cancer surgery, laser techniques, minimally invasive cosmetic surgery, and emerging techniques. Building on the highly successful first edition, this volume provides much expanded coverage of a range of topics. The best information is provided to reveal the most appropriate interventions for particular indications, optimal treatment techniques, and strategies for avoiding adverse events. Evidence-Based Procedural Dermatology, 2nd edition, includes two types of chapters: procedures and indications. Each chapter is designed to be clear and concise, with tables and flowcharts to showcase main findings. Each cited study is tagged with a level of evidence, and every recommendation includes a strength of evidence score. More than double the length of the first edition, this newest edition includes added procedures and interventions like: new lasers and energy devices for skin resurfacing and pigmentation; non-invasive fat reduction and skin tightening using cryolipolysis, radiofrequency, ultrasound, and chemical adipocytolysis; specific post-skin cancer excision reconstruction techniques; and novel approaches for melanoma.

Carotenoids are a group of approximately 600 compounds synthesized by photosynthetic organisms. These pigments are abundant in fruits and vegetables, as well as in certain animal products such as eggs and salmon, being responsible for their colorful appearance. The bioactive properties of certain carotenoids in human health are clear, as some of these compounds have antioxidant properties and serve as the only precursors of vitamin A in nature. The aim of this Special Issue entitled “Carotenoids and Human Health” is to provide the scientific community with an updated perspective of this exciting and growing research area. We compiled 19 papers from some of the most prominent scientists in the carotenoid field, including seven literature reviews and 12 original publication, covering topics such as cancer, obesity, vision, cognitive function, and skin health.

It is estimated that 80 percent of women have some degree of cellulite. Although there are no permanent solutions for cellulite, dermatologists recognize that this is an issue of importance for many women. This guide reviews current research on the pathophysiology and treatment of cellulite, as well as the many recent developments in medical therap

The book will educate and decode the role of vitamins, essential fatty acids and other nutraceuticals on skin health and their tremendous impact to the current needs of the skin care industry. Focus on conditions, as acne, dermatitis, dry scaly skin or alopecia will provide a comprehensive knowledge of the relationship of nutrition and skin as well as the current attempts in nutritional or dermatological research. It will stimulate food professionals to brainstorm for new products and opportunities that will target the emerging antiaging and wellness trends and modern consumer needs.

"The purpose of this book is to show how cosmeceuticals (defined as a skin care product with bioactive ingredients, which have a desired effect on the skin) work for a variety of skin care concerns, and in concert with cosmetic procedures commonly used by dermatologists and cosmetic physicians"--

Reviews the recent breakthroughs in vitamin A research. Discusses the metabolism of vitamin A; the mechanism of action of vitamin A and the provitamin A carotenoids; the role of retinoids in embryonic development, skin and epithelial cells, blood cells, vision, and reproduction; vitamin A deficiency and teratogenicity; and the anticancer role of vitamin A from an epidemiological point of view. Intended as a source of information for scientists engaged in research in the field of vitamin A.