Gene Control, Second Edition

Gene Control, Second Edition
  • Author : David Latchman
  • Publisher : Garland Science
  • Pages : 528
  • Relase : 2015-02-20
  • ISBN : 9781317407751

Gene Control, Second Edition Book Review:

The new edition of Gene Control has been updated to include significant advances in the roles of the epigenome and regulatory RNAs in gene regulation. The chapter structure remains the same: the first part consists of pairs of chapters that explain the mechanisms involved and how they regulate gene expression, and the second part deals with specific biological processes (including diseases) and how they are controlled by genes. Coverage of methodology has been strengthened by the inclusion more explanation and diagrams.The significant revision and updating will allow Gene Control to continue to be of value to students, scientists and clinicians interested in the topic of gene control.

Gene Control

Gene Control
  • Author : David Latchman
  • Publisher : Garland Science
  • Pages : 448
  • Relase : 2018-03-29
  • ISBN : 9781136844201

Gene Control Book Review:

Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition. The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and post-transcriptional processes. Three pairs of chapters deal with each of these aspects, first describing the basic process itself, followed by the manner in which it is involved in controlling gene expression. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo. Another chapter discusses the key roles played by gene-regulatory processes in the specification of differentiated cell types such as muscle cells and neurons. The final chapters discuss the consequences of errors in gene control; the relationship between gene misregulation and human diseases, especially cancer; and potential therapies designed specifically to target particular levels of gene control. Gene Control will be of value to students in biological sciences, as well as to scientists and clinicians interested in how genes are regulated in health and disease.

Mechanisms of Gene Regulation

Mechanisms of Gene Regulation
  • Author : Carsten Carlberg,Ferdinand Molnár
  • Publisher : Springer Science & Business Media
  • Pages : 210
  • Relase : 2013-12-11
  • ISBN : 9789400779051

Mechanisms of Gene Regulation Book Review:

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule which states that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.

Post-Transcriptional Gene Regulation

Post-Transcriptional Gene Regulation
  • Author : Jane Wu
  • Publisher : John Wiley & Sons
  • Pages : 280
  • Relase : 2013-04-24
  • ISBN : 9783527665419

Post-Transcriptional Gene Regulation Book Review:

Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.

A Genetic Switch

A Genetic Switch
  • Author : Mark Ptashne
  • Publisher : CSHL Press
  • Pages : 172
  • Relase : 2004
  • ISBN : 0879697164

A Genetic Switch Book Review:

The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This newly updated third edition focuses once again solely on phage, incorporating the most recent insights into gene expression in prokaryotes while retaining all the special qualities of the original edition

Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
  • Author : David T. Curiel
  • Publisher : Academic Press
  • Pages : 868
  • Relase : 2016-03-10
  • ISBN : 9780128005101

Adenoviral Vectors for Gene Therapy Book Review:

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

The Selfish Gene

The Selfish Gene
  • Author : Richard Dawkins,Charles Simonyi Professor of the Public Understanding of Science Richard Dawkins,David Dawkins,RICHARD AUTOR DAWKINS
  • Publisher : Oxford University Press, USA
  • Pages : 352
  • Relase : 1989
  • ISBN : 0192860925

The Selfish Gene Book Review:

An ethologist shows man to be a gene machine whose world is one of savage competition and deceit

Elsevier's Integrated Review Biochemistry

Elsevier's Integrated Review Biochemistry
  • Author : John W. Pelley
  • Publisher : Elsevier Health Sciences
  • Pages : 214
  • Relase : 2011-11-30
  • ISBN : 9780323074469

Elsevier's Integrated Review Biochemistry Book Review:

Rev. ed. of: Elsevier's integrated biochemistry / John W. Pelley. c2007.

Genomic Control Process

Genomic Control Process
  • Author : Isabelle Peter,Eric H. Davidson
  • Publisher : Academic Press
  • Pages : 460
  • Relase : 2015-01-21
  • ISBN : 9780124047464

Genomic Control Process Book Review:

Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type Demonstrates the causal power of system-level understanding of genomic control process Conceptually organizes a constellation of complex and diverse biological phenomena Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Pages : 482
  • Relase : 2015-10-19
  • ISBN : 9780128004715

Epigenetic Gene Expression and Regulation Book Review:

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science

Transcriptional Regulation in Eukaryotes

Transcriptional Regulation in Eukaryotes
  • Author : Michael Carey,Michael F. Carey,Stephen T. Smale
  • Publisher : CSHL Press
  • Pages : 640
  • Relase : 2000
  • ISBN : 0879696354

Transcriptional Regulation in Eukaryotes Book Review:

In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.

Gene Regulation

Gene Regulation
  • Author : David Latchman
  • Publisher : Garland Science
  • Pages : 359
  • Relase : 2007-01-25
  • ISBN : 9780203016336

Gene Regulation Book Review:

Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Molecular Biology

Molecular Biology
  • Author : David P. Clark,Nanette J. Pazdernik
  • Publisher : Elsevier
  • Pages : 928
  • Relase : 2012-03-20
  • ISBN : 9780123785954

Molecular Biology Book Review:

Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture. NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. Fully revised art program

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher :
  • Pages :
  • Relase : 2004
  • ISBN : 0815332181

Molecular Biology of the Cell Book Review:

Molecular Biology of B Cells

Molecular Biology of B Cells
  • Author : Tasuku Honjo,Michael Reth,Andreas Radbruch,Frederick Alt
  • Publisher : Elsevier
  • Pages : 600
  • Relase : 2014-10-09
  • ISBN : 9780123984906

Molecular Biology of B Cells Book Review:

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response

MicroRNA

MicroRNA
  • Author : Jaishree Paul,Rohini Muthuswami
  • Publisher : CRC Press
  • Pages : 202
  • Relase : 2018-02-19
  • ISBN : 9781351679879

MicroRNA Book Review:

This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.

Epigenetics

Epigenetics
  • Author : C. David Allis
  • Publisher : CSHL Press
  • Pages : 502
  • Relase : 2007-01
  • ISBN : 9780879697242

Epigenetics Book Review:

The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

Gene Structure and Expression

Gene Structure and Expression
  • Author : John D. Hawkins,Hawkins John D.
  • Publisher : Cambridge University Press
  • Pages : 212
  • Relase : 1996-09-12
  • ISBN : 0521568668

Gene Structure and Expression Book Review:

This third edition of a successful textbook is a concise description of the structure and function of genes.

RNA Polymerases as Molecular Motors

RNA Polymerases as Molecular Motors
  • Author : Robert Landick,Terence Strick,Jue Wang
  • Publisher : Royal Society of Chemistry
  • Pages : 252
  • Relase : 2021-11-23
  • ISBN : 9781839160660

RNA Polymerases as Molecular Motors Book Review:

To thrive, every living cell must continuously gauge and respond to changes in its environment. These changes are ultimately implemented by modulating gene expression, a process that relies on transcription by Nature’s most multivalent molecular machine, the RNA polymerase. This book covers progress made over the past decade understanding how this machine functions to compute the cellular state, from the atomistic structural level responsible for chemistry to the integrative level at which RNA polymerase interacts with the other key molecular machineries of the cell.

The Plasma Proteins

The Plasma Proteins
  • Author : Frank W. Putnam
  • Publisher :
  • Pages : 418
  • Relase : 1987
  • ISBN : UOM:39015013202216

The Plasma Proteins Book Review:

The Plasma Proteins V5 ...