Epic Measures One Doctor Seven Billion Patients

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time—the groundbreaking program to answer the most essential question for humanity: how do we live and die?—and the visionary mastermind behind it. Medical doctor and economist Christopher Murray began the Global Burden of Disease studies to gain a truer understanding of how we live and how we die. While it is one of the largest scientific projects ever attempted—as breathtaking as the first moon landing or the Human Genome Project—the questions it answers are meaningful for every one of us: What are the world’s health problems? Who do they hurt? How much? Where? Why? Murray argues that the ideal existence isn’t simply the longest but the one lived well and with the least illness. Until we can accurately measure how people live and die, we cannot understand what makes us sick or do much to improve it. Challenging the accepted wisdom of the WHO and the UN, the charismatic and controversial health maverick has made enemies—and some influential friends, including Bill Gates who gave Murray a $100 million grant. In Epic Measures, journalist Jeremy N. Smith offers an intimate look at Murray and his groundbreaking work. From ranking countries’ healthcare systems (the U.S. is 37th) to unearthing the shocking reality that world governments are funding developing countries at only 30% of the potential maximum efficiency when it comes to health, Epic Measures introduces a visionary leader whose unwavering determination to improve global health standards has already changed the way the world addresses issues of health and wellness, sets policy, and distributes funding.

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time—the groundbreaking program to answer the most essential question for humanity: how do we live and die?—and the visionary mastermind behind it. Medical doctor and economist Christopher Murray began the Global Burden of Disease studies to gain a truer understanding of how we live and how we die. While it is one of the largest scientific projects ever attempted—as breathtaking as the first moon landing or the Human Genome Project—the questions it answers are meaningful for every one of us: What are the world’s health problems? Who do they hurt? How much? Where? Why? Murray argues that the ideal existence isn’t simply the longest but the one lived well and with the least illness. Until we can accurately measure how people live and die, we cannot understand what makes us sick or do much to improve it. Challenging the accepted wisdom of the WHO and the UN, the charismatic and controversial health maverick has made enemies—and some influential friends, including Bill Gates who gave Murray a $100 million grant. In Epic Measures, journalist Jeremy N. Smith offers an intimate look at Murray and his groundbreaking work. From ranking countries’ healthcare systems (the U.S. is 37th) to unearthing the shocking reality that world governments are funding developing countries at only 30% of the potential maximum efficiency when it comes to health, Epic Measures introduces a visionary leader whose unwavering determination to improve global health standards has already changed the way the world addresses issues of health and wellness, sets policy, and distributes funding.

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time—the groundbreaking program to answer the most essential question for humanity: how do we live and die?—and the visionary mastermind behind it. Medical doctor and economist Christopher Murray began the Global Burden of Disease studies to gain a truer understanding of how we live and how we die. While it is one of the largest scientific projects ever attempted—as breathtaking as the first moon landing or the Human Genome Project—the questions it answers are meaningful for every one of us: What are the world’s health problems? Who do they hurt? How much? Where? Why? Murray argues that the ideal existence isn’t simply the longest but the one lived well and with the least illness. Until we can accurately measure how people live and die, we cannot understand what makes us sick or do much to improve it. Challenging the accepted wisdom of the WHO and the UN, the charismatic and controversial health maverick has made enemies—and some influential friends, including Bill Gates who gave Murray a $100 million grant. In Epic Measures, journalist Jeremy N. Smith offers an intimate look at Murray and his groundbreaking work. From ranking countries’ healthcare systems (the U.S. is 37th) to unearthing the shocking reality that world governments are funding developing countries at only 30% of the potential maximum efficiency when it comes to health, Epic Measures introduces a visionary leader whose unwavering determination to improve global health standards has already changed the way the world addresses issues of health and wellness, sets policy, and distributes funding.

This taut, true thriller dives into a dark world that touches us all, as seen through the brilliant, breakneck career of an extraordinary hacker--a woman known only as Alien. When she arrived at MIT in the 1990s, Alien was quickly drawn to the school's tradition of high‑risk physical trespassing: the original "hacking." Within a year, one of her hallmates was dead and two others were arraigned. Alien's adventures were only just beginning. After a stint at the storied, secretive Los Alamos National Laboratory, Alien was recruited by a top cybersecurity firm where she deployed her cache of virtual weapons--and the trespassing and social engineering talents she had developed while "hacking" at MIT. The company tested its clients' security by every means possible--not just coding, but donning disguises and sneaking past guards and secretaries into the C‑suite. Alien now runs a boutique hacking outfit that caters to some of the world's biggest and most vulnerable institutions--banks, retailers, government agencies. Her work combines devilish charm, old‑school deception, and next generation spycraft. In Breaking and Entering, cybersecurity finally gets the rich, character‑driven, fast-paced treatment it deserves.

* Finalist for the PEN/E. O. Wilson Literary Science Writing Award * Washington Post Notable Book of the Year * People Magazine Best Book of the Year * Shelf Awareness Best Book of the Year * "Extraordinary and courageous . . . No doubt if everyone were to read this book, the world would change."---New York Times Book Review New York Times-bestselling author Ron Powers offers a searching, richly researched narrative of the social history of mental illness in America paired with the deeply personal story of his two sons' battles with schizophrenia. From the centuries of torture of "lunatiks" at Bedlam Asylum to the infamous eugenics era to the follies of the anti-psychiatry movement to the current landscape in which too many families struggle alone to manage afflicted love ones, Powers limns our fears and myths about mental illness and the fractured public policies that have resulted. Braided with that history is the moving story of Powers's beloved son Kevin--spirited, endearing, and gifted--who triumphed even while suffering from schizophrenia until finally he did not, and the story of his courageous surviving son Dean, who is also schizophrenic. A blend of history, biography, memoir, and current affairs ending with a consideration of where we might go from here, this is a thought-provoking look at a dreaded illness that has long been misunderstood.

Span style="font-style:italic;"It's Enough to Make You Sick explains how the American health care system developed and how it has deteriorated into a national disgrace. Lobosky indicts the special interests who have played a role in the demise of American health care, examines the current attempts at reform, and offers a practical, compassionate blueprint for effective change.

"[A] resolute, detailed, and unflinching review of [Annan’s] most difficult hours…No one ever came closer to being the voice of “we the peoples” and no one paid a higher price for it. The world still needs such a voice, but the next person who tries to fill that role will want to reflect long and hard on the lessons of this candid, courageous, and unsparing memoir." --Michael Ignatieff, The New York Review of Books Receiving the Nobel Peace Prize in December 2001, United Nations Secretary-General Kofi Annan spoke to a world still reeling from the terrorist attacks of September 11. “Ladies and Gentlemen,” proclaimed Annan, “we have entered the third millennium through a gate of fire. If today, after the horror of 11 September, we see better, and we see further—we will realize that humanity is indivisible. New threats make no distinction between races, nations, or regions.” Yet within only a few years the world was more divided than ever—polarized by the American invasion of Iraq, the Arab-Israeli conflict, the escalating civil wars in Africa, and the rising influence of China. Interventions: A Life in War and Peace is the story of Annan’s remarkable time at the center of the world stage. After forty years of service at the United Nations, Annan shares here his unique experiences during the terrorist attacks of September 11; the American invasions of Iraq and Afghanistan; the war between Israel, Hizbollah, and Lebanon; the brutal conflicts of Somalia, Rwanda, and Bosnia; and the geopolitical transformations following the end of the Cold War. With eloquence and unprecedented candor, Interventions finally reveals Annan’s unique role and unparalleled perspective on decades of global politics. The first sub-Saharan African to hold the position of Secretary-General, Annan has led an extraordinary life in his own right. His idealism and personal politics were forged in the Ghanaian independence movement of his adolescence, when all of Africa seemed to be rising as one to demand self-determination. Schooled in Africa, Europe, and the United States, Annan ultimately joined the United Nations in Geneva at the lowest professional level in the still young organization. Annan rose rapidly through the ranks and was by the end of the Cold War prominently placed in the dramatically changing department of peacekeeping operations. His stories of Presidents Clinton and Bush, dictators like Saddam Hussein and Robert Mugabe, and public figures of all stripes contrast powerfully with Annan’s descriptions of the courage and decency of ordinary people everywhere struggling for a new and better world. Showing the successes of the United Nations, Annan also reveals the organization’s missed opportunities and ongoing challenges—inaction in the Rwanda genocide, continuing violence between Israelis and Palestinians, and the endurance of endemic poverty. Yet Annan’s great strength in this book is his ability to embed these tragedies within the context of global politics, demonstrating how, time and again, the nations of the world have retreated from the UN’s founding purpose. From the pinnacle of global politics, Annan made it his purpose to put the individual at the center of every mission for peace and prosperity. A personal biography of global statecraft, Annan’s Interventions is as much a memoir as a guide to world order—past, present, and future.

During the last twenty years, the interest in public health leadership has continued to increase with the need to strengthen the infrastructure of public health, the events of September 11, 2001, the health reform movement, scientific breakthroughs, the increasing role for primary care programs in the public health agenda, and the increasing deficit at the federal, state, and local level. Since the publication of the first edition in 2003, Public Health Leadership: Putting Principles Into Practice has become a standard reference for future and practicing public health leaders. In five parts, it explores the basic theories and principles of leadership and then describes how they may be applied in the public health setting. Leadership skills and competencies, as well as methods for measuring and evaluating leaders are all thoroughly covered.This new third editioin is an exhaustive revision that now includes extensive coverage of the leadership skills and tools that are critical to managing public health emergencies. It also offers:* Updated exercises and case studies throughout* New chapter on Building Infrastructure, * New chapter on Accreditation, * New chapter on the Global Public Health Leader* New accompanying online Instructor's Manual with over 100 references on leadership, additional case studies, curriculum guide, toolkit, and additional exercises.

"If you're as interested in Japan as I am, I think you'll find that The Power to Compete is a smart and thought-provoking look at the future of a fascinating country." - Bill Gates, "5 Books to Read This Summer" Father and son – entrepreneur and economist – search for Japan's economic cure The Power to Compete tackles the issues central to the prosperity of Japan – and the world – in search of a cure for the "Japan Disease." As founder and CEO of Rakuten, one of the world's largest Internet companies, author Hiroshi Mikitani brings an entrepreneur's perspective to bear on the country's economic stagnation. Through a freewheeling and candid conversation with his economist father, Ryoichi Mikitani, the two examine the issues facing Japan, and explore possible roadmaps to revitalization. How can Japan overhaul its economy, education system, immigration, public infrastructure, and hold its own with China? Their ideas include applying business techniques like Key Performance Indicators to fix the economy, using information technology to cut government bureaucracy, and increasing the number of foreign firms with a head office in Japan. Readers gain rare insight into Japan's future, from both academic and practical perspectives on the inside. Mikitani argues that Japan's tendency to shun international frameworks and hide from global realities is the root of the problem, while Mikitani Sr.'s background as an international economist puts the issue in perspective for a well-rounded look at today's Japan. Examine the causes of Japan's endless economic stagnation Discover the current efforts underway to enhance Japan's competitiveness Learn how free market "Abenomics" affected Japan's economy long-term See Japan's issues from the perspective of an entrepreneur and an economist Japan's malaise is seated in a number of economic, business, political, and cultural issues, and this book doesn't shy away from hot topics. More than a discussion of economics, this book is a conversation between father and son as they work through opposing perspectives to help their country find The Power to Compete.

From the Pulitzer Prize–winning author of The Looming Tower, and the pandemic novel The End of October: an unprecedented, momentous account of Covid-19—its origins, its wide-ranging repercussions, and the ongoing global fight to contain it "A book of panoramic breadth ... managing to surprise us about even those episodes we … thought we knew well … [With] lively exchanges about spike proteins and nonpharmaceutical interventions and disease waves, Wright’s storytelling dexterity makes all this come alive.” —The New York Times Book Review From the fateful first moments of the outbreak in China to the storming of the U.S. Capitol to the extraordinary vaccine rollout, Lawrence Wright’s The Plague Year tells the story of Covid-19 in authoritative, galvanizing detail and with the full drama of events on both a global and intimate scale, illuminating the medical, economic, political, and social ramifications of the pandemic. Wright takes us inside the CDC, where a first round of faulty test kits lost America precious time . . . inside the halls of the White House, where Deputy National Security Adviser Matthew Pottinger’s early alarm about the virus was met with confounding and drastically costly skepticism . . . into a Covid ward in a Charlottesville hospital, with an idealistic young woman doctor from the town of Little Africa, South Carolina . . . into the precincts of prediction specialists at Goldman Sachs . . . into Broadway’s darkened theaters and Austin’s struggling music venues . . . inside the human body, diving deep into the science of how the virus and vaccines function—with an eye-opening detour into the history of vaccination and of the modern anti-vaccination movement. And in this full accounting, Wright makes clear that the medical professionals around the country who’ve risked their lives to fight the virus reveal and embody an America in all its vulnerability, courage, and potential. In turns steely-eyed, sympathetic, infuriated, unexpectedly comical, and always precise, Lawrence Wright is a formidable guide, slicing through the dense fog of misinformation to give us a 360-degree portrait of the catastrophe we thought we knew.

A people-centered approach to global health When People Come First critically assesses the expanding field of global health. It brings together an international and interdisciplinary group of scholars to address the medical, social, political, and economic dimensions of the global health enterprise through vivid case studies and bold conceptual work. The book demonstrates the crucial role of ethnography as an empirical lantern in global health, arguing for a more comprehensive, people-centered approach. Topics include the limits of technological quick fixes in disease control, the moral economy of global health science, the unexpected effects of massive treatment rollouts in resource-poor contexts, and how right-to-health activism coalesces with the increased influence of the pharmaceutical industry on health care. The contributors explore the altered landscapes left behind after programs scale up, break down, or move on. We learn that disease is really never just one thing, technology delivery does not equate with care, and biology and technology interact in ways we cannot always predict. The most effective solutions may well be found in people themselves, who consistently exceed the projections of experts and the medical-scientific, political, and humanitarian frameworks in which they are cast. When People Come First sets a new research agenda in global health and social theory and challenges us to rethink the relationships between care, rights, health, and economic futures.

The acclaimed author of Pandora’s Lunchbox and former New York Times reporter delivers an “entertaining and highly useful book that gives you the tools to understand how alternative medicine works, so you can confidently make up your own mind” (The Washington Post). We all know someone who has had a seemingly miraculous cure from an alternative form of medicine: a friend whose chronic back pain vanished after sessions with an acupuncturist or chiropractor; a relative with digestive issues who recovered with herbal remedies; a colleague whose autoimmune disorder went into sudden inexplicable remission thanks to an energy healer or healing retreat. The tales are far too common to be complete fabrications, yet too anecdotal and outside the medical mainstream to be taken seriously scientifically. How do we explain them and the growing popularity of alternative medicine more generally? In The Magic Feather Effect, author and journalist Melanie Warner takes us on a vivid, important journey through the world of alternative medicine. Visiting prestigious research clinics and ordinary people’s homes, she investigates the scientific underpinning for the purportedly magical results of these practices and reveals not only the medical power of beliefs and placebo effects, but also the range, limits, and uses of the surprising system of self-healing that resides inside us. Equal parts helpful, illuminating, and compelling, The Magic Feather Effect is a “well-written survey of alternative medicine…fair-minded, thorough, and focused on verifiable scientific research” (Publishers Weekly, starred review). Warner’s enlightening, engaging deep dive into the world of alternative medicine and the surprising science that explains why it may work is an essential read.

Recipient of the 2015 PEN New England Award for Nonfiction “The arrival of a significant young nonfiction writer . . . A measured yet bravura performance.” —Dwight Garner, The New York Times James Joyce’s big blue book, Ulysses, ushered in the modernist era and changed the novel for all time. But the genius of Ulysses was also its danger: it omitted absolutely nothing. Joyce, along with some of the most important publishers and writers of his era, had to fight for years to win the freedom to publish it. The Most Dangerous Book tells the remarkable story surrounding Ulysses, from the first stirrings of Joyce’s inspiration in 1904 to the book’s landmark federal obscenity trial in 1933. Written for ardent Joyceans as well as novices who want to get to the heart of the greatest novel of the twentieth century, The Most Dangerous Book is a gripping examination of how the world came to say Yes to Ulysses.

An NPR Best Book of 2017 "[Teeth is] . . . more than an exploration of a two-tiered system—it is a call for sweeping, radical change." —New York Times Book Review "Show me your teeth," the great naturalist Georges Cuvier is credited with saying, "and I will tell you who you are." In this shattering new work, veteran health journalist Mary Otto looks inside America's mouth, revealing unsettling truths about our unequal society. Teeth takes readers on a disturbing journey into America's silent epidemic of oral disease, exposing the hidden connections between tooth decay and stunted job prospects, low educational achievement, social mobility, and the troubling state of our public health. Otto's subjects include the pioneering dentist who made Shirley Temple and Judy Garland's teeth sparkle on the silver screen and helped create the all-American image of "pearly whites"; Deamonte Driver, the young Maryland boy whose tragic death from an abscessed tooth sparked congressional hearings; and a marketing guru who offers advice to dentists on how to push new and expensive treatments and how to keep Medicaid patients at bay. In one of its most disturbing findings, Teeth reveals that toothaches are not an occasional inconvenience, but rather a chronic reality for millions of people, including disproportionate numbers of the elderly and people of color. Many people, Otto reveals, resort to prayer to counteract the uniquely devastating effects of dental pain. Otto also goes back in time to understand the roots of our predicament in the history of dentistry, showing how it became separated from mainstream medicine, despite a century of growing evidence that oral health and general bodily health are closely related. Muckraking and paradigm-shifting, Teeth exposes for the first time the extent and meaning of our oral health crisis. It joins the small shelf of books that change the way we view society and ourselves—and will spark an urgent conversation about why our teeth matter.

From Giller Prize winner, internationally acclaimed, and bestselling author Vincent Lam comes a superbly crafted, highly suspenseful, and deeply affecting novel set against the turmoil of the Vietnam War. Percival Chen is the headmaster of the most respected English school in Saigon. He is also a bon vivant, a compulsive gambler and an incorrigible womanizer. He is well accustomed to bribing a forever-changing list of government officials in order to maintain the elite status of the Chen Academy. He is fiercely proud of his Chinese heritage, and quick to spot the business opportunities rife in a divided country. He devotedly ignores all news of the fighting that swirls around him, choosing instead to read the faces of his opponents at high-stakes mahjong tables. But when his only son gets in trouble with the Vietnamese authorities, Percival faces the limits of his connections and wealth and is forced to send him away. In the loneliness that follows, Percival finds solace in Jacqueline, a beautiful woman of mixed French and Vietnamese heritage, and Laing Jai, a son born to them on the eve of the Tet offensive. Percival's new-found happiness is precarious, and as the complexities of war encroach further and further into his world, he must confront the tragedy of all he has refused to see. Blessed with intriguingly flawed characters moving through a richly drawn historical and physical landscape, The Headmaster's Wager is a riveting story of love, betrayal and sacrifice.

This report reviews engineering's importance to human, economic, social and cultural development and in addressing the UN Millennium Development Goals. Engineering tends to be viewed as a national issue, but engineering knowledge, companies, conferences and journals, all demonstrate that it is as international as science. The report reviews the role of engineering in development, and covers issues including poverty reduction, sustainable development, climate change mitigation and adaptation. It presents the various fields of engineering around the world and is intended to identify issues and challenges facing engineering, promote better understanding of engineering and its role, and highlight ways of making engineering more attractive to young people, especially women.--Publisher's description.

In 2009, Swine Flu reminded us that pandemics still happen, and award- winning journalist Alan Sipress reminds us that far worse could be brewing. When a highly lethal strain of avian flu broke out in Asia in 2003 and raced westward, Sipress, as a reporter for The Washington Post, tracked the virus across nine countries, watching its secrets elude the world's brightest scientists and most intrepid disease hunters. A vivid portrayal of the struggle between man and microbe, The Fatal Strain is a fast-moving account that weaves cultural, political, and scientific strands into a tale of inevitable pandemic.

National Book Award Finalist: “This man’s ideas may be the most influential, not to say controversial, of the second half of the twentieth century.”—Columbus Dispatch At the heart of this classic, seminal book is Julian Jaynes's still-controversial thesis that human consciousness did not begin far back in animal evolution but instead is a learned process that came about only three thousand years ago and is still developing. The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion—and indeed our future. “Don’t be put off by the academic title of Julian Jaynes’s The Origin of Consciousness in the Breakdown of the Bicameral Mind. Its prose is always lucid and often lyrical…he unfolds his case with the utmost intellectual rigor.”—The New York Times “When Julian Jaynes . . . speculates that until late in the twentieth millennium BC men had no consciousness but were automatically obeying the voices of the gods, we are astounded but compelled to follow this remarkable thesis.”—John Updike, The New Yorker “He is as startling as Freud was in The Interpretation of Dreams, and Jaynes is equally as adept at forcing a new view of known human behavior.”—American Journal of Psychiatry

LONGLISTED 2015 – International IMPAC Dublin Literary Award The Circle is the exhilarating new novel from Dave Eggers, bestselling author of A Hologram for the King, a finalist for the National Book Award. When Mae Holland is hired to work for the Circle, the world’s most powerful internet company, she feels she’s been given the opportunity of a lifetime. The Circle, run out of a sprawling California campus, links users’ personal emails, social media, banking, and purchasing with their universal operating system, resulting in one online identity and a new age of civility and transparency. As Mae tours the open-plan office spaces, the towering glass dining facilities, the cozy dorms for those who spend nights at work, she is thrilled with the company’s modernity and activity. There are parties that last through the night, there are famous musicians playing on the lawn, there are athletic activities and clubs and brunches, and even an aquarium of rare fish retrieved from the Marianas Trench by the CEO. Mae can’t believe her luck, her great fortune to work for the most influential company in the world—even as life beyond the campus grows distant, even as a strange encounter with a colleague leaves her shaken, even as her role at the Circle becomes increasingly public. What begins as the captivating story of one woman’s ambition and idealism soon becomes a heart-racing novel of suspense, raising questions about memory, history, privacy, democracy, and the limits of human knowledge.

Wall Street Journal Bestseller New York Times bestselling author Dan Heath explores how to prevent problems before they happen, drawing on insights from hundreds of interviews with unconventional problem solvers. So often in life, we get stuck in a cycle of response. We put out fires. We deal with emergencies. We stay downstream, handling one problem after another, but we never make our way upstream to fix the systems that caused the problems. Cops chase robbers, doctors treat patients with chronic illnesses, and call-center reps address customer complaints. But many crimes, chronic illnesses, and customer complaints are preventable. So why do our efforts skew so heavily toward reaction rather than prevention? Upstream probes the psychological forces that push us downstream—including “problem blindness,” which can leave us oblivious to serious problems in our midst. And Heath introduces us to the thinkers who have overcome these obstacles and scored massive victories by switching to an upstream mindset. One online travel website prevented twenty million customer service calls every year by making some simple tweaks to its booking system. A major urban school district cut its dropout rate in half after it figured out that it could predict which students would drop out—as early as the ninth grade. A European nation almost eliminated teenage alcohol and drug abuse by deliberately changing the nation’s culture. And one EMS system accelerated the emergency-response time of its ambulances by using data to predict where 911 calls would emerge—and forward-deploying its ambulances to stand by in those areas. Upstream delivers practical solutions for preventing problems rather than reacting to them. How many problems in our lives and in society are we tolerating simply because we’ve forgotten that we can fix them?